Topical finasteride with minoxidil
Why use topical finasteride with minoxidil?
Topical finasteride can be combined with topical minoxidil in a single solution in order to simplify the process of administering these two highly effective hair loss treatments.
When topical finasteride is combined with topical minoxidil, the two drugs are thought to act synergistically. When treating hair loss they act differently: minoxidil helps hair growth by widening blood vessels in the scalp, promoting better blood flow to hair follicles and stimulating growth. In contrast, finasteride works by blocking the action of the potent male hormone dihydrotestosterone or “DHT”, which is crucial for hair follicle health.
Topical finasteride with minoxidil mainly targets the scalp area, reducing systemic absorption and associated risks and side effects.
The way in which your topical finasteride with minoxidil is delivered through the skin and targeted to the hair follicle is of great importance. In order to be clinically effective and minimise side effects, it is crucial that the medication absorbs well through the skin, reaches its target destination in the hair follicle and remains there with minimal systemic absorption into the bloodstream.
Dr Ball has researched the various formulations of topical finasteride that are available through specialist compounding pharmacies and has identified a product that is very well tolerated, contains no propylene glycol and has a pleasant aroma and feel on the hair. It is delivered to the hair follicle through a solution known as TrichoSol™.
TrichoSol™ is applied to the scalp in drops from a pipette and rubbed into the scalp. You can read more about Dr Ball’s recommended product in our TrichoSol™ blog here.
Please see the finasteride patient leaflet for information regarding potential side effects from topical finasteride.
Adverse effects of topical minoxidil may include:
- Local redness, itching, and flaking. However, skin reactions are largely due to the presence of propylene glycol in minoxidil solution and propylene glycol is not present in our recommended TrichoSol formula. Treatment should be discontinued if there is persistent redness or irritation of the scalp.
- Increased hair shedding, which generally occurs 2–6 weeks after initiating treatment. It is temporary and subsides within a few weeks. Treatment should be discontinued if shedding persists for more than 2 weeks.
- Hypertrichosis (unwanted non-scalp hair, including facial hair growth). This is caused by the transfer of the product to areas other than the scalp. We advise that care should be taken to apply the product to just the scalp. Applying a head covering can limit unwanted spreading of the product.
- Hypotension (low blood pressure) has been rarely reported, although there is no clear increased risk of cardiovascular complications with the use of topical minoxidil (because systemic absorption through normal skin is very low). Treatment should be discontinued if hypotension is detected.
It is also recommended to discontinue treatment and seek medical advice if any of the following occur:
- Chest pain.
- Tachycardia.
- Syncope.
- Dizziness.
- Sudden unexplained weight gain.
- Swollen hands or feet.
- Persistent redness or irritation of the scalp.
- Other unexpected new symptoms.
Apply 1ml once or twice a day to the areas of thinning (depending on prescribed strength).
Please always follow the instructions on your prescription.
| Strength | Application | Cost per day |
|---|---|---|
| Topical finasteride 0.25% with minoxidil 5% – 100ml bottle | 1ml once daily | £0.61 |
| Topical finasteride 0.25% with minoxidil 7% – 100ml bottle | 1ml once daily | £0.63 |
| Topical finasteride 0.1% with minoxidil 5% – 100ml bottle | 1ml twice daily | £1.03 |
| Topical finasteride 0.1% with minoxidil 7% – 100ml bottle | 1ml twice daily | £1.13 |